Dog DNA Testing Explained: How It Fits Into Your Puppy’s Complete Health Screening
- Sheila Markazi
- Dec 5, 2025
- 4 min read
When you are ready to bring a new puppy into your home, understanding the health information provided by breeders can feel overwhelming. You might hear terms like dog DNA health testing, OFA health testing, or CHIC certification thrown around. These are important tools, but they serve different purposes. Knowing how to interpret them will help you choose a responsible dog breeder and avoid common pitfalls.
This post will explain what canine genetic testing can and cannot do, why OFA health testing remains essential, and how both work together to give you a clearer picture of your puppy’s health. By the end, you will feel more confident about how to choose a dog breeder who prioritizes comprehensive, breed-specific health screening.
What Puppy DNA Health Testing Does Well
Dog DNA testing companies like Embark and Wisdom Panel offer genetic panels that analyze a dog’s DNA from a simple cheek swab. These tests have become popular because they provide valuable insights into inherited diseases, coat color traits, and genetic diversity.
Inherited Disease Identification
These panels screen for dozens or even hundreds of genetic mutations linked to specific diseases. For example, in Labrador Retrievers, tests can detect mutations related to exercise-induced collapse or progressive retinal atrophy. This helps breeders avoid mating two carriers and reduces the risk of affected puppies.
Coat Color and Trait Information
Many buyers enjoy knowing their puppy’s potential coat colors or patterns. Genetic panels can predict these traits accurately, which is useful for breed enthusiasts.
Genetic Diversity Metrics
Some tests provide information about a dog’s genetic diversity or inbreeding levels. This helps breeders maintain healthier bloodlines by avoiding closely related pairings.
Despite these strengths, puppy DNA health testing has limits. It only detects conditions caused by known genetic mutations. Many important health issues do not have a simple DNA marker.
Why OFA Health Testing Remains Essential
The Orthopedic Foundation for Animals (OFA) offers health screening that focuses on structural and functional evaluations. These include exams for hips, elbows, patellas (knees), cardiac health, and eyes through CAER (Canine Eye Registration Foundation) evaluations.
Structural Health Exams
X-rays and specialist evaluations detect conditions like hip dysplasia, elbow dysplasia, and patellar luxation. These problems often develop from a combination of genetics and environment, so DNA tests alone cannot predict them.
Cardiac Evaluations
Heart conditions require specialist exams such as echocardiograms. These cannot be identified through DNA testing.
Eye Exams
CAER eye exams screen for inherited and acquired eye diseases that may not have a known genetic marker.
For example, in breeds like Golden Retrievers or German Shepherds, hip dysplasia is a common concern. While DNA tests might screen for some genetic markers, OFA health testing through X-rays is the gold standard to assess joint health.

Common Misunderstandings: “DNA Tested Parents” Does Not Mean Complete Health Screening
Some breeders advertise puppies as coming from “DNA tested parents” as if this covers all health concerns. This is misleading because:
DNA tests do not replace specialist exams like OFA hips or cardiac evaluations.
Many conditions, especially orthopedic and cardiac, cannot be detected by DNA alone.
Relying solely on DNA tests ignores the importance of physical exams and imaging.
This misunderstanding can lead buyers to believe a puppy is fully health-screened when critical tests are missing. A reputable dog breeder will use both canine genetic testing and OFA health testing to provide a complete health profile.
Examples of Breeds That Need Both Genetic and OFA Testing
Labrador Retrievers
Genetic panels screen for inherited diseases like exercise-induced collapse, but OFA testing is essential for hips and elbows.
Golden Retrievers
DNA tests help identify genetic diseases, but hip and elbow dysplasia screening through OFA is critical.
Boxers
Cardiac exams are vital due to breed-specific heart conditions, alongside DNA testing for inherited diseases.
Border Collies
Genetic testing covers many inherited diseases, but patella and eye exams are necessary for full health evaluation.
How DNA Tests and OFA Health Testing Work Together
DNA tests and OFA health testing are complementary tools that you can use in your search for a happy, healthy puppy. Together, they provide a fuller picture of a puppy’s health:
DNA tests identify specific inherited mutations and traits.
OFA health testing evaluates physical health and structural soundness.
CHIC certification often requires a combination of these tests, showing a commitment to comprehensive screening.
When breeders meet CHIC requirements, they demonstrate responsible breeding practices by using both genetic and physical health evaluations.
What Responsible Dog Breeders Typically Use
Reputable dog breeders combine multiple health screening methods to reduce the risk of inherited and acquired conditions. They will:
Perform puppy DNA health testing to identify carriers of genetic diseases.
Complete OFA health testing for hips, elbows, patellas, cardiac health, and eyes.
Provide documentation of all test results and certifications.
Explain the limitations of each test honestly.
Follow breed-specific health recommendations from national breed clubs or the AKC.
When you ask a breeder about health testing, look for clear, detailed answers and proof of testing. Avoid breeders who rely solely on “DNA tested parents” without additional exams.
How to Choose a Dog Breeder Using Health Testing Information
Ask for copies of OFA health testing results and DNA test reports.
Verify if the breeder participates in CHIC certification or similar programs.
Research breed-specific health concerns and recommended tests.
Watch for red flags like vague answers or refusal to share health information.
Choose breeders who explain how they use both genetic and physical health tests to improve their breeding program.
Final Thoughts on Evaluating Puppy Health Information
Understanding the difference between puppy DNA health testing and OFA health testing helps you make informed decisions. Both are important and work best together. DNA tests identify inherited mutations, while OFA exams assess structural and specialist health issues that DNA cannot detect.
When you look for AKC puppies or puppies from responsible dog breeders, expect transparency and comprehensive health screening. This approach protects your puppy’s future and supports ethical breeding practices.
Your next step is to ask breeders detailed questions about their health testing protocols. This knowledge will help you find a healthy, well-bred puppy to welcome into your life. For those who don’t have the time to sort through breeder websites or chase down health testing details, Puppy Due Diligence offers a comprehensive research service. I handle the outreach, gather the information, and deliver a concise report with all the essentials you need. Explore my services to learn more.



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